Drug resistance and combating drug resistance in cancer
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چکیده
منابع مشابه
Combating and overcoming drug resistance in cancer
While the majority of patients with cancer treated with chemotherapy initially respond to treatment, a sub-group of patients either do not respond or eventually stop responding to the therapy in a phenomenon known as tumor cell resistance. Evidence of many different mechanisms of resistance have been reported in the literature, and it remains a great challenge to delineate the pathways involved...
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Metabolic alterations, driven by genetic and epigenetic factors, have long been known to be associated with the etiology of cancer. Furthermore, accumulating evidence suggest that cancer metabolism is intimately linked to drug resistance, which is currently one of the most important challenges in cancer treatment. Altered metabolic pathways help cancer cells to proliferate at a rate higher than...
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ژورنال
عنوان ژورنال: Cancer Drug Resistance
سال: 2019
ISSN: 2578-532X
DOI: 10.20517/cdr.2019.10